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| Advances in the Biological Effects of Exosomes on Tumors and Their Detection Methods |
| SONG Yu-meng1,2,ZHAI Rui2,LEI Xi-mei1,CHU Zhan-ying2,ZHU Man-man2,FAN Xiao-xue1,2,YE Zi-hong1,DAI Xin-hua2,FANG Xiang2 |
1. Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine,College of Life Sciences,China Jiliang University,Hangzhou,Zhejiang 310018,China
2.Technology Innovation Center of Mass Spectrometry for State Market Regulation,Center for Advanced Measurement Science,National Institute of Metrology,Beijing 100029,China |
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Abstract Exosomes are tiny vesicles secreted by cells, which contain important biologically active substances such as proteins, lipids, and nucleic acids. As an important carrier of cell-to-cell communication, exosomes directly participate in the occurrence and development of tumors in the body, and by affecting the tumor microenvironment, they mediate the growth and migration of tumor cells. Due to the special physiological functions of exosomes, in recent years, there has been an increasing number of studies using them as treatment vectors and biomarkers for major diseases, and the detection methods for exosomes have also been continuously developed. A systematic review was conducted on the recent research of the biological functions and detection of exosomes from tumor cells, and the development trend of detection methods was prospected.
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Received: 06 September 2021
Published: 25 June 2023
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| Fund:The National Key R&D Program of China |
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2023, Vol. 44 
