Acta Metrologica Sinica  2021, Vol. 42 Issue (8): 1094-1100    DOI: 10.3969/j.issn.1000-1158.2021.08.18
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Evaluation of Measurement Uncertainty in the Determination of Psoralen, Lsopsoralen, Neobavaisoflavone and Bavachin in Cosmetics
FAN Fei1,HUANG Jiong-li2,AN Qing1,CUI Ying1,ZHU Qing1
1. Xi'an Institute for Food and Drug Control, Xi'an, Shaanxi 710054, China;
2. Xi'an Institute of Measurement and Testing Technology, Xi'an, Shaanxi 710068, China
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Abstract  Uncertainties from the determination procedure of neobavaisoflavone, bavachin, psoralen and lsopsoralen in cosmetics by high performance liquid chromatography (HPLC) were assessed. The mathematical model was established, and each source and uncertainty component were analyzed. The standard uncertainty and expanded uncertainty were reported at last. The results showed that the expanded uncertainties were 1.65μg/g, 1.82μg/g, 1.66μg/g and 1.61μg/g (95% confidence level, k=2), when the content of neobavaisoflavone, bavachin, psoralen and lsopsoralen in cosmetics were 42.61μg/g, 44.04μg/g, 42.94μg/g and 41.90μg/g. The main sources for the uncertainty were discussed, and suggestions for improvement were also introduced.
Key wordsmetrology      cosmetic ingredients testing      neobavaisoflavone      bavachin      psoralen      lsopsoralen      uncertainty     
Received: 09 April 2019      Published: 20 August 2021
PACS:  TB99  
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FAN Fei
HUANG Jiong-li
AN Qing
CUI Ying
ZHU Qing
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FAN Fei,HUANG Jiong-li,AN Qing, et al. Evaluation of Measurement Uncertainty in the Determination of Psoralen, Lsopsoralen, Neobavaisoflavone and Bavachin in Cosmetics[J]. Acta Metrologica Sinica, 2021, 42(8): 1094-1100.
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http://jlxb.china-csm.org:81/Jwk_jlxb/EN/10.3969/j.issn.1000-1158.2021.08.18     OR     http://jlxb.china-csm.org:81/Jwk_jlxb/EN/Y2021/V42/I8/1094
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