2019新型冠状病毒的抗原抗体检测

doi:10.3969/j.issn.1000-1158.2020.05.01

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Abstract 2019 novel coronavirus (SARS-CoV-2) invades the human body and causes an acute respiratory infectious disease, which was named as Corona Virus Disease (COVID-19). The global spread of SARS-Cov-2 poses a huge threat to global public health security. The detection of SARS-CoV-2 is particularly important for disease diagnosis. Immunoassay method has played a role in clinical diagnosis as an aid to virus nucleic acid detection. Immuno-diagnostic techniques include antibody and antigen detection, and determine whether the virus are carried by detecting the viruss own protein and antibody. Analysis was focused on the current immunoassay methods for SARS-CoV-2.

Key words： metrology 2019-nCoV/SARS-Cov-2 COVID-19 antigen antibody immunoassay method detection

Received: 16 March 2020 Published: 14 May 2020

PACS:

TB99

Fund:The National Key Research and Development Program of China

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	Articles by authors
	GAO Yuan
	CHEN Chuan
	WANG Jing

Cite this article:

GAO Yuan,CHEN Chuan,WANG Jing. Antigen and Antibody Detection of SARS-CoV-2[J]. Acta Metrologica Sinica, 2020, 41(5): 513-517.

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http://jlxb.china-csm.org:81/Jwk_jlxb/EN/10.3969/j.issn.1000-1158.2020.05.01 OR http://jlxb.china-csm.org:81/Jwk_jlxb/EN/Y2020/V41/I5/513

［1］Ramaiah A, Arumugaswami V. Insights into Cross-species Evolution of Novel HumanCoronavirus 2019-nCoV and Defining Immune Determinants for Vaccine Development［J］. bioRxiv, 2020. https://doi.org/10.1101/2020.01.29.925867.
［2］张永卓, 王晶, 傅博强, 等. 2019新型冠状病毒的核酸检测［J］.计量学报, 2020, 41(4): 393-398.
Zhang Y Z, Wang J,Fu B Q, et al. Nucleic Acid Detection of the SARS-CoV-2［J］.Acta Metrologica Sinica, 2020,41(4): 393-398.

［3］Shen M Z, Zhou Y, Ye J W, et al. Recent advances and perspectives of nucleic acid detection forcoronavirus［J］. Journal of Pharmaceutical Analysis, 2020. https://doi.org/10.1016/j.jpha.2020.02.010.
［4］Peng L, Liu J, Xu W X, et al. 2019 Novel Coronavirus can be detected in urine, blood, anal swabs and oropharyngeal swabs samples［J］. medRxiv. https://doi.org/10.1101/2020.02.21.20026179.
［5］Zhou P, Yang X L, Wang X G, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin ［J］. Nature, 2020, 579: 270-273.
［6］Xiao S Y, Wu Y, Liu H. Evolving status of the 2019 novel coronavirus infection: Proposal of conventional serologic assays for disease diagnosis and infection monitoring ［J］. Journal of Medical Virology, 2020, 92(5):1-4.
［7］Jia X, Zhang P, Tian Y. Clinical significance of IgM and IgG test for diagnosis of highly suspected COVID-19 infection［J］. medRxiv. https://doi.org/10.1101/2020.02.28.20029025.
［8］Zhao J, Yuan Q, Wang H, et al. Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019［J］. medRxiv. https://doi.org/10.1101/2020.03.02.20030189.
［9］Zhang J, Liu J, Li N, et al. Serological detection of 2019-nCoV respond to the epidemic: A useful complement to nucleic acid testing［J］. medRxiv. https://doi.org/10.1101/2020.03.04.20030916.
［10］Cai X, Chen J, Hu J, et al. A Peptide-based Magnetic Chemiluminescence Enzyme Immunoassay for Serological Diagnosis of Corona Virus Disease 2019 (COVID-19) ［J］. medRxiv.https://doi.org/10.1101/2020.02.22.20026617.
［11］Li M, Jin R, Peng Y, et al. Generation of antibodies against COVID-19 virus for development of diagnostic tools ［J］. medRxiv. https://doi.org/10.1101/2020.02.20.20025999.
［12］Wan Y S, Shang J, Graham R, et al. Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS ［J］. Journal of Virology,2020,doi:10. 1128/JVI. 00127-20.

［13］Lei C H, Fu W Y, Qian K W, et al. Potent neutralization of 2019 novel coronavirus by recombinant ACE2-Ig ［J］. bioRxiv.https://doi.org/10.1101/2020.02.01.929976.
［14］Tian X L, Li C, Huang A L, et al. Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody［J］. bioRxiv. https://doi.org/10.1101/2020.01.28.923011.

［15］Xiang J, Yan M, Li H, et al. Evaluation of Enzyme-Linked Immunoassay and Colloidal GoldImmunochroma-tographic Assay Kit for Detection of Novel Coronavirus (SARS-Cov-2) Causing an Outbreak of Pneumonia (COVID-19) ［J］. medRxiv. https://doi.org/10.1101/2020.01.29.925867.